Design of a Flow-through Polarographic Sensor Based on Metal Films for Determining N-nitrosodiethanolamine Levels in Rabbit Biological Fluids
نویسندگان
چکیده
The construction and characterization of a flow-through polarographic detector for catalyzing the electroreduction of N-nitrosodiethanolamine (NDELA), is discussed. The flow-through cell is equipped with a gold wire electrode (a thin mercury film deposited on a gold substance). The response is evaluated with respect to substance diameter, length, concentration of modifying film, operating potential, supporting electrolyte and pH, and flow rate in the DC mode. The system allows the determination of N-nitrosodiethanolamine in rabbit biological fluids with relatively inexpensive equipment.
منابع مشابه
Monitoring nitrite, N-nitrosodiethanolamine, and mutagenicity in cutting fluids used in the metal industry.
We carried out an integrated environmental/biological monitoring program to evaluate cancer hazards among metal industry workers exposed to cutting fluids. Several cutting fluids were sampled according to response to a semiquantitative nitrite rapid test in metal factories in central Italy. The nitrite-positive samples were analyzed for nitrite and nitrosodiethanolamine (NDELA) content and muta...
متن کاملDesign and Fabrication of PVC Membrane Electrode Based on Netural Ligand (E)-N'-(1-(2-Hydroxyphenyl)Ethylidene)Benzohydrazi for Teramadol hydrochloride Measurement in Drugs and Biological Fluids
Here, a simple, quick, Low cost and sensitive Potentiometric method is described for tramadol hydrochloride measurement using .PVC membrane electrode based on neutral ligand (E)-N'-(1-(2-hydroxyphenyl)ethylidene)benzohydrazid. Besides, effect of various parameters like ionic additives, membrane solvent and pH on the Potentiometric response of the electrode are investigated. The best electrode p...
متن کاملDisposable single-use electrochemical sensor: A novel hollow fiber based tool for environmental monitoring of cadmium
The objective of this study is to design a simple, fast, sensitive and single-use electrode with the simultaneous capability of preconcentration and measuring, for application in a three-electrode voltammetry system to identify and measure the heavy metal cadmium. The design process of this sensor consists of several stages. The polyurethane foam and multi walled carbon nanotubes nanoparticles ...
متن کاملBiological monitoring of workers exposed to N-nitrosodiethanolamine in the metal industry.
Biological monitoring of occupational hazards was performed in workers using cutting fluids containing N-nitrosodiethanolamine (NDELA). The study involved a group of 25 male subjects from some metal factories in central Italy who used cutting fluids with an NDELA content of > or = 5 mg/l (high-exposure group) and a group of 37 males exposed to cutting fluids with an NDELA content < 5 mg/l (low-...
متن کاملDesign and fabrication of a rapid conductometric pH sensor based on metal-oxide technology
A micro-fabricated metal-oxide based conductometric pH sensor is designed and fabricated in this manuscript. pH sensors have applications in various areas from farming to food processing, human health monitoring, industrial waste products investigation, etc. Accordingly, there is a relatively high demand for a reliable, rapid and precise pH sensor in the market. Relatively precise pH sensors ha...
متن کامل